Nitrazepam is not proposed to be used in These under 18 a long time of age. Use in very younger small children may be In particular dangerous. Children addressed with nitrazepam for epilepsies may well establish tolerance inside months of ongoing use, with dose escalation normally occurring with extended use. Sleepiness, deterioration in motor skil

Dette derivatet kan acetyleres, hydroksyleres og glukuronideres. Cytokrom P-450 inkludert CYP3A kan spille en viktig rolle i reduksjon og oksidasjon av klonazepam. Eliminasjonshalveringstiden for klonazepam er vanligvis thirty til forty timer. Farmakokinetikken til klonazepam er doseuavhengig i hele doseringsområdet. Det er ingen bevis for at klon

Antakelig er det best egnet som tilleggsmedikasjon i noen uker dersom en pasient har behov for å bytte antiepileptikum. Det er likevel aldri blitt dokumentert misbruk eller tilvenning av klonazepam hos epilepsipasienter. Klonazepam har trolig også effekt på nevrotransmitteren serotonin, og det er derfor postulert at medikamentet kan ha en særli

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